What is Bretazenil?

Bretazenil (Ro 16-6028) is a synthetic imidazobenzodiazepine supplied as a high-purity reference material for in-vitro and analytical work. It is a partial agonist at the benzodiazepine site of the GABA-A receptor that binds across α1–α6 subunit-containing subtypes, and is studied as a non-selective partial-agonist reference compound.

Specifications

• Chemical name: tert-butyl (13aS)-8-bromo-9-oxo-11,12,13,13a-tetrahydro-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylate
• Synonyms: Ro 16-6028
• CAS number: 84379-13-5
• Molecular formula: C19H20BrN3O3
• Molecular weight: 418.29 g/mol
• Class: imidazobenzodiazepine
• Form: crystalline solid
• Available sizes: 100 mg · 250 mg · 500 mg
• Storage: keep sealed, cool, dry and away from light

In research settings Bretazenil is used as a reference compound in GABA-A receptor pharmacology and benzodiazepine-site partial-agonism studies.

Quality & documentation: every batch is third-party tested; a current Certificate of Analysis is available on request.

Shipping: plain, unbranded packaging shipped from the Netherlands across the EU.

For laboratory research use only. Not for human or veterinary consumption. Buyers must be 18+.