What is CL-218,872?

CL-218,872 is a synthetic triazolopyridazine supplied as a high-purity reference material for in-vitro and analytical work. It was one of the first non-benzodiazepine ligands shown to be selective for the α1 (BZ1) subtype of the GABA-A receptor, and remains a widely cited tool compound for distinguishing benzodiazepine-receptor subtypes.

Specifications

• Chemical name: 3-methyl-6-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[3,4-f]pyridazine
• Class: triazolopyridazine
• CAS number: 66548-69-4
• Molecular formula: C13H9F3N4
• Molecular weight: 278.24 g/mol
• Form: crystalline solid
• Available sizes: 100 mg · 250 mg · 500 mg
• Storage: keep sealed, cool, dry and away from light

In research settings CL-218,872 is used as a reference compound for α1-subtype-selective GABA-A receptor studies and benzodiazepine-site characterisation.

Quality & documentation: every batch is third-party tested; a current Certificate of Analysis is available on request.

Shipping: plain, unbranded packaging shipped from the Netherlands across the EU.

For laboratory research use only. Not for human or veterinary consumption. Buyers must be 18+.